This book deals with the subject Rasa Shastra and Bhaishajya kalpana containing the course curriculum for the Second Professional BAMS students. This book is structured based on the syllabus prescribed by NCISM and it includes the contents of Paper II Ayurvediya Aushadhi Prayoga Vigyana. The highlights of the book are: • The topics are dealt with point wise narration and tabulation done for easy and quick grasping. • The chapters are presented comprehensively, integrating analytical, logical, and descriptive approaches, along with clearly defined learning outcomes. • The text describes the Concept-Analysis- Application of the subject Bhaishajya prayoga as per the Course Outcome & Programme Outcome. • Research updates of the drugs and preparations are highlighted in this text along with the Research Process &Outcome. • Each chapter is meticulously enhanced with examination-oriented content that includes Short Answer Questions, Long Answer Questions, and Multiple-Choice Questions. This book serves as a ready reckoner for the second professional BAMS students, Rasa Shastra and Bhaishajya kalpana PG & Ph.D. scholars to learn Rasa Shastra and Bhaishajya kalpana. It will become an indispensable academic resource and a guiding tool for both learners and educators.